ASIC1

Across TCGA patient cohorts, ASIC1 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,708 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ASIC1-associated proteins across cancer lineages are GDAP1_S11, GTF3C2, and HLA-E. Each is linked with ASIC1 in more than 3 cancer types. Because this analysis shows association rather than direction, both ASIC1-to-partner and partner-to-ASIC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ASIC1 versus GDAP1_S11 in LSCC, with a Pearson correlation of 0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ASIC1→partner) and Y-score (partner→ASIC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GDAP1_S11 →	+0.449	+0.352	.002	.007	3	4
LSCC	GTF3C2 →	+0.329	+0.830	<.001	<.001	3	4
GBM	HLA-E →	-0.486	-0.856	<.001	.008	3	4
LSCC	RPRD1B →	+0.271	+0.540	<.001	<.001	3	4
OV	SNRPD3 →	+0.222	+0.665	.007	.002	3	3
LSCC	MAP1A →	+0.479	+0.609	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,708 associations by consensus.

ASIC1 vs GDAP1_S11 — LSCC

Explore this scatter interactively →