ASIC1

Across TCGA patient cohorts, ASIC1 protein abundance is significantly associated with the protein abundance of many other proteins, with 7,513 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ASIC1-associated proteins across cancer lineages are BCR, ARNT2, and ARPC1B. Each is linked with ASIC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ASIC1-to-partner and partner-to-ASIC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ASIC1 versus BCR in GBM, with a Pearson correlation of 0.44.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ASIC1→partner) and Y-score (partner→ASIC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	BCR →	+0.457	+0.749	<.001	<.001	3	2
GBM	ARNT2 →	+0.252	+0.596	<.001	<.001	3	1
GBM	ARPC1B →	-0.464	-0.545	<.001	<.001	3	1
GBM	ARPC2 →	-0.159	-0.514	<.001	<.001	3	1
GBM	ARPC3 →	-0.160	-0.489	<.001	<.001	3	1
GBM	ARPC5 →	-0.232	-0.486	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,513 associations by consensus.

ASIC1 vs BCR — GBM

Explore this scatter interactively →