ASF1A

Across TCGA cell cohorts, ASF1A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,710 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ASF1A-associated GO terms across cancer lineages are DNA replication-dependent chromatin assembly, Transcription elongation-coupled chromatin remodeling, and DNA repair-dependent chromatin remodeling. Each is linked with ASF1A in more than 16 cancer types. Because this analysis shows association rather than direction, both ASF1A-to-partner and partner-to-ASF1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication-dependent chromatin assembly grouped by ASF1A-low versus ASF1A-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ASF1A→partner) and Y-score (partner→ASF1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	DNA replication-dependent chromatin assembly →	+0.122	+0.901	.001	.001	3	17
BONE	Transcription elongation-coupled chromatin remodeling →	+0.155	+1.110	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	DNA repair-dependent chromatin remodeling →	+0.088	+0.870	<.001	.001	3	15
OESOPHAGUS	Transcription elongation by RNA polymerase II →	+0.093	+0.843	.006	.004	3	12
LUNG_SCLC	Protein-DNA complex assembly →	+0.081	+1.103	<.001	<.001	3	12
LUNG_SCLC	DNA-templated DNA replication maintenance of fidelity →	+0.111	+0.977	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,710 associations by consensus.

DNA replication-dependent chromatin assembly by ASF1A expression — KIDNEY

Explore this box plot interactively →