ASCL5

Across TCGA patient cohorts, ASCL5 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,088 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ASCL5-associated proteins across cancer lineages are HNRNPLL, PARP1, and POGK. Each is linked with ASCL5 in more than 4 cancer types. Because this analysis shows association rather than direction, both ASCL5-to-partner and partner-to-ASCL5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ASCL5 versus HNRNPLL in HNSC, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ASCL5→partner) and Y-score (partner→ASCL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	HNRNPLL →	+0.282	+0.808	<.001	<.001	3	5
HNSC	PARP1 →	+0.474	+0.769	<.001	<.001	3	4
OV	POGK →	+0.391	+0.752	<.001	.007	3	4
LSCC	WRNIP1 →	+0.357	+0.563	<.001	<.001	3	4
GBM	ZFR →	+0.213	+0.468	.003	.001	3	4
UCEC	SPRY1 →	-0.916	-1.044	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,088 associations by consensus.

ASCL5 vs HNRNPLL — HNSC

Explore this scatter interactively →