ASCL5

Across TCGA cell cohorts, ASCL5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,093 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ASCL5-associated GO terms across cancer lineages are Regulation of myoblast fusion, Regulation of syncytium formation by plasma membrane fusion, and Cytoplasmic translation. Each is linked with ASCL5 in more than 14 cancer types. Because this analysis shows association rather than direction, both ASCL5-to-partner and partner-to-ASCL5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by ASCL5-low versus ASCL5-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ASCL5→partner) and Y-score (partner→ASCL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of myoblast fusion →	+0.133	+0.552	<.001	<.001	3	15
OESOPHAGUS	Regulation of syncytium formation by plasma membrane fusion →	+0.131	+0.577	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Cytoplasmic translation →	+0.106	+0.264	<.001	<.001	2	14
UPPER_AERODIGESTIVE_TRACT	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile →	+0.067	+0.235	<.001	.001	3	12
UPPER_AERODIGESTIVE_TRACT	mRNA splicing, via spliceosome →	+0.067	+0.235	<.001	.001	3	12
OESOPHAGUS	Oxidative phosphorylation →	+0.109	+0.451	.003	.002	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,093 associations by consensus.

Regulation of myoblast fusion by ASCL5 expression — OESOPHAGUS

Explore this box plot interactively →