ASCC3

Across TCGA cell cohorts, ASCC3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,910 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ASCC3-associated GO terms across cancer lineages are DNA alkylation repair, Ribosome disassembly, and 7-methylguanosine mRNA capping. Each is linked with ASCC3 in more than 18 cancer types. Because this analysis shows association rather than direction, both ASCC3-to-partner and partner-to-ASCC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA alkylation repair grouped by ASCC3-low versus ASCC3-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ASCC3→partner) and Y-score (partner→ASCC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	DNA alkylation repair →	+0.140	+0.804	<.001	<.001	3	19
BREAST	Ribosome disassembly →	+0.077	+1.106	.001	<.001	3	12
LUNG_NSCLC_LUSC	7-methylguanosine mRNA capping →	+0.130	+0.702	.001	.002	2	13
LUNG_NSCLC_LUSC	7-methylguanosine RNA capping →	+0.130	+0.702	.001	.002	2	13
LUNG_NSCLC_LUAD	Cytoplasmic translational elongation →	+0.078	+0.642	<.001	<.001	3	11
STOMACH	Ribosome-associated ubiquitin-dependent protein catabolic process →	+0.144	+0.880	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,910 associations by consensus.

DNA alkylation repair by ASCC3 expression — PANCREAS

Explore this box plot interactively →