ASCC3

Across TCGA pan-cancer cohorts, ASCC3 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of ASCC3’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where ASCC3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ASCC3 is over-expressed in tumor.

KIRP, HNSC, and KIRC are the cancer types where ASCC3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ASCC3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	All	II,III,IV	+1.107	<.001	11	view →
HNSC	Male	All	+1.008	<.001	11	view →
KIRC	Male	All	+0.703	<.001	11	view →
STAD	Male	II,III,IV	+1.109	<.001	10	view →
LUAD	Male	All	+0.870	<.001	9	view →
COAD	Male	All	+0.845	<.001	9	view →
LUSC	Female	All	+0.893	<.001	8	view →
LIHC	Female	III,IV	+1.316	<.001	7	view →
BLCA	All	III,IV	+0.723	.001	7	view →
BRCA	All	II,III,IV	+0.553	<.001	6	view →
THCA	All	All	+0.369	.001	4	view →
CHOL	All	All	+1.073	.018	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

ASCC3–KIRP

Open the KIRP breakdown →