ASCC3

Across TCGA cell cohorts, ASCC3 protein abundance is significantly associated with the go_rna of many other GO terms, with 3,232 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ASCC3-associated GO terms across cancer lineages are Regulation of lipid biosynthetic process, Clathrin coat assembly, and Modulation by symbiont of entry into host. Each is linked with ASCC3 in more than 4 cancer types. Because this analysis shows association rather than direction, both ASCC3-to-partner and partner-to-ASCC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of lipid biosynthetic process grouped by ASCC3-low versus ASCC3-high in LUNG_SCLC.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ASCC3→partner) and Y-score (partner→ASCC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of lipid biosynthetic process →	+0.074	+0.647	<.001	<.001	3	5
LUNG_NSCLC_LUSC	Clathrin coat assembly →	-0.151	-1.730	.003	<.001	3	5
BLOOD_Lymphoma	Modulation by symbiont of entry into host →	+0.192	+0.860	<.001	<.001	3	5
BLOOD_Lymphoma	Double-strand break repair via break-induced replication →	-0.166	-0.710	<.001	.003	3	5
LUNG_NSCLC_LUAD	Primary alcohol metabolic process →	+0.142	+0.453	<.001	<.001	3	5
BLOOD_Lymphoma	Startle response →	-0.236	-0.680	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,232 associations by consensus.

Regulation of lipid biosynthetic process by ASCC3 expression — LUNG_SCLC

Explore this box plot interactively →