ASB11

Across TCGA patient cohorts, ASB11 mutation is significantly associated with the RNA expression of many other genes, with 4,510 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ASB11-associated genes across cancer lineages are RPS29P32, MIR548AL, and KDM5DP1. Each is linked with ASB11 in more than 1 cancer types. Because this analysis shows association rather than direction, both ASB11-to-partner and partner-to-ASB11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPS29P32 grouped by ASB11-low versus ASB11-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ASB11→partner) and Y-score (partner→ASB11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPS29P32 →	+0.360	+2.084	<.001	.002	3	2
LUSC	MIR548AL →	+0.348	+5.081	<.001	.004	3	2
LUSC	KDM5DP1 →	+0.143	+4.882	<.001	.005	3	2
LUAD	RNU1-75P →	+0.307	+3.821	.009	.007	3	2
UCEC	LINC02876 →	+0.085	+1.789	.005	.003	3	2
UCEC	RNA5SP287 →	+0.177	+2.600	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,510 associations by consensus.

RPS29P32 by ASB11 expression — UCEC

Explore this box plot interactively →