ASAP1-IT2

Across TCGA pan-cancer cohorts, ASAP1-IT2 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated ASAP1-IT2 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher ASAP1-IT2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ASAP1-IT2 expression acts as an unfavorable survival marker, although some lineages such as BRCA and LUSC show a favorable association.

KIRC, BRCA, and LIHC are the cancer types where ASAP1-IT2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.508	0.720	<.001	124	view →
BRCA	DFS	Median	All	0.552	0.486	<.001	78	view →
LIHC	OS	Median	All	0.408	0.603	<.001	71	view →
ACC	OS	Median	All	0.421	0.886	.002	71	view →
UVM	DFS	Tertile	III,IV	0.153	0.858	<.001	70	view →
THCA	DFS	Quartile	II,III,IV	0.691	0.945	.005	24	view →
UCEC	DFS	Tertile	All	0.521	0.700	.017	18	view →
LGG	DFS	Median	All	0.793	0.865	.004	13	view →
DLBC	DFS	Median	III,IV	0.140	0.917	.010	10	view →
KIRP	OS	Median	All	0.526	0.789	.005	10	view →
KICH	OS	Median	III,IV	0.467	0.941	.006	8	view →
COAD	DFS	Median	IV	0.284	0.654	.021	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

ASAP1-IT2–KIRC (OS)

Open the KIRC breakdown →