ASAP1-IT2

Across TCGA pan-cancer cohorts, ASAP1-IT2 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of ASAP1-IT2’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where ASAP1-IT2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ASAP1-IT2 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

HNSC, KIRC, and STAD are the cancer types where ASAP1-IT2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ASAP1-IT2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	All	+0.109	<.001	10	view →
KIRC	All	All	+0.112	<.001	8	view →
STAD	All	All	+0.280	.010	4	view →
LIHC	Male	All	+0.077	.006	4	view →
READ	All	All	+0.155	.003	2	view →
CHOL	All	All	+0.140	.015	2	view →
THCA	Male	All	+0.065	.021	1	view →
COAD	All	All	+0.043	.019	1	view →
KICH	All	All	−0.032	.042	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

ASAP1-IT2–HNSC

Open the HNSC breakdown →