Across TCGA patient cohorts, ASAH2B mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ASAH2B-associated genes across cancer lineages are MIR6780A, MIR8078, and MIR8075. Each is linked with ASAH2B in more than 1 cancer types. Because this analysis shows association rather than direction, both ASAH2B-to-partner and partner-to-ASAH2B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ASAH2B→partner) and Y-score (partner→ASAH2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6780A →	+0.702	+3.386	<.001	.008	3	1
UCEC	MIR8078 →	+0.852	+3.106	<.001	.007	3	1
UCEC	MIR8075 →	+0.940	+3.863	.007	.003	3	1
COAD	RN7SL392P →	+0.167	+7.741	<.001	.009	3	1
UCEC	MIR629 →	+0.360	+4.260	<.001	.007	3	1
UCEC	IGHD3-16 →	+1.610	+3.417	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Exploration

ASAH2B survival (RNA) · tumor vs normal (RNA) · all ASAH2B data types