Across TCGA patient cohorts, ASAH2 protein abundance is significantly associated with the RNA expression of many other genes, with 197 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ASAH2-associated genes across cancer lineages are RNF24, KLF8, and TYRP1. Each is linked with ASAH2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ASAH2-to-partner and partner-to-ASAH2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ASAH2→partner) and Y-score (partner→ASAH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	RNF24 →	-0.569	-0.756	.005	.002	3	1
PDAC	KLF8 →	-0.454	-0.929	.001	.001	3	1
PDAC	TYRP1 →	-0.626	-0.988	.006	.002	3	1
PDAC	EHBP1 →	-0.664	-1.037	.008	<.001	3	1
PDAC	EXTL3 →	-0.342	-0.658	.001	.009	3	1
PDAC	AP5S1 →	-0.382	-1.019	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 197 associations by consensus.

Exploration

ASAH2 survival (RNA) · tumor vs normal (RNA) · all ASAH2 data types