ARX

Across TCGA patient cohorts, ARX RNA expression is significantly associated with the protein abundance of many other proteins, with 7,612 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible ARX-associated proteins across cancer lineages are SYNPO, TNXB, and WIPF3. Each is linked with ARX in more than 2 cancer types. Because this analysis shows association rather than direction, both ARX-to-partner and partner-to-ARX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARX versus SYNPO in PDAC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ARX→partner) and Y-score (partner→ARX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	SYNPO →	+0.363	+0.472	<.001	<.001	3	3
OV	TNXB →	+0.644	+0.639	<.001	<.001	3	3
OV	WIPF3 →	+0.852	+0.870	<.001	<.001	3	3
OV	PRKAR2B →	+0.650	+0.831	<.001	<.001	3	3
BRCA	CAB39L →	+0.566	+0.773	<.001	<.001	3	3
OV	COL18A1 →	+0.336	+0.620	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,612 associations by consensus.

ARX vs SYNPO — PDAC

Explore this scatter interactively →