ARX

Across TCGA patient cohorts, ARX protein abundance is significantly associated with the RNA expression of many other genes, with 2,624 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ARX-associated genes across cancer lineages are RNU6-108P, PPIAP23, and KLK8. Each is linked with ARX in more than 1 cancer types. Because this analysis shows association rather than direction, both ARX-to-partner and partner-to-ARX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARX versus RNU6-108P in UCEC, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARX→partner) and Y-score (partner→ARX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-108P →	+2.190	+2.144	.002	<.001	3	1
UCEC	PPIAP23 →	+0.152	+1.901	.008	.005	3	1
GBM	KLK8 →	+0.068	+0.498	<.001	.003	3	1
GBM	STAC2 →	+1.651	+0.426	.001	.009	3	1
GBM	NEUROD1 →	-1.892	-0.464	.003	.008	3	1
GBM	CSF2 →	-0.381	-0.511	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,624 associations by consensus.

ARX vs RNU6-108P — UCEC

Explore this scatter interactively →