ARX

Across TCGA patient cohorts, ARX mutation is significantly associated with the RNA expression of many other genes, with 854 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARX-associated genes across cancer lineages are RNU6-822P, RNU6-906P, and LINC02789. Each is linked with ARX in more than 1 cancer types. Because this analysis shows association rather than direction, both ARX-to-partner and partner-to-ARX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-822P grouped by ARX-low versus ARX-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARX→partner) and Y-score (partner→ARX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	RNU6-822P →	+0.235	+5.149	<.001	.003	3	2
LIHC	RNU6-906P →	+0.329	+5.305	<.001	.003	3	2
LIHC	LINC02789 →	+0.014	+6.495	<.001	<.001	3	2
CESC	CDKN2AIPNLP1 →	+0.172	+3.885	.003	.007	3	2
LUAD	RPS29P2 →	+0.303	+6.739	<.001	<.001	3	2
COAD	MIR1305 →	+0.505	+5.003	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 854 associations by consensus.

RNU6-822P by ARX expression — LIHC

Explore this box plot interactively →