ART4

Across TCGA patient cohorts, ART4 protein abundance is significantly associated with the RNA expression of many other genes, with 4,472 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ART4-associated genes across cancer lineages are PTGDS, FHL5, and C7. Each is linked with ART4 in more than 2 cancer types. Because this analysis shows association rather than direction, both ART4-to-partner and partner-to-ART4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ART4 versus PTGDS in PDAC, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ART4→partner) and Y-score (partner→ART4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	PTGDS →	+0.980	+0.679	<.001	.001	3	3
PDAC	FHL5 →	+0.837	+0.611	.007	.002	3	3
PDAC	C7 →	+1.422	+0.568	.008	.007	3	3
PDAC	ITIH3 →	+0.548	+0.377	<.001	.004	3	3
PDAC	MFAP4 →	+1.159	+0.765	.002	<.001	3	3
LUAD	PPP1R14A →	+0.889	+0.433	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,472 associations by consensus.

ART4 vs PTGDS — PDAC

Explore this scatter interactively →