ART4

Across TCGA cell cohorts, ART4 RNA expression is significantly associated with the go_rna of many other GO terms, with 758 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ART4-associated GO terms across cancer lineages are Neutrophil mediated cytotoxicity, Neutrophil-mediated killing of symbiont cell, and Regulation of cellular response to vascular endothelial growth factor stimulus. Each is linked with ART4 in more than 2 cancer types. Because this analysis shows association rather than direction, both ART4-to-partner and partner-to-ART4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Neutrophil mediated cytotoxicity grouped by ART4-low versus ART4-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ART4→partner) and Y-score (partner→ART4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Neutrophil mediated cytotoxicity →	-0.847	-0.052	.002	<.001	3	3
KIDNEY	Neutrophil-mediated killing of symbiont cell →	-0.847	-0.052	.002	<.001	3	3
LIVER	Regulation of cellular response to vascular endothelial growth factor stimulus →	+0.186	+1.735	.004	.005	3	3
LIVER	Endosome membrane tubulation →	+0.171	+1.802	.003	.001	3	3
BREAST	Positive regulation of cytoplasmic translational initiation →	+0.086	+0.160	.006	.006	3	3
BLOOD_Leukemia	Phospholipase C/protein kinase C signal transduction →	-0.292	-0.361	.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 758 associations by consensus.

Neutrophil mediated cytotoxicity by ART4 expression — KIDNEY

Explore this box plot interactively →