ART1

Across TCGA patient cohorts, ART1 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. COAD shows the largest number of these associations.

The most reproducible ART1-associated genes across cancer lineages are Adipocytes, Astrocytes, and naive B-cells. Each is linked with ART1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ART1-to-partner and partner-to-ART1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Adipocytes grouped by ART1-low versus ART1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ART1→partner) and Y-score (partner→ART1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Adipocytes →	+0.040	+3.431	.016	.020	3	2
COAD	Astrocytes →	+0.047	+2.692	.019	.048	3	2
HNSC	naive B-cells →	+0.017	+2.819	<.001	.018	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Adipocytes by ART1 expression — COAD

Explore this box plot interactively →