ARSJ

Across TCGA cell cohorts, ARSJ RNA expression is significantly associated with the go_rna of many other GO terms, with 5,563 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ARSJ-associated GO terms across cancer lineages are Neuropilin signaling pathway, Protein localization to early endosome, and Regulation of cell-matrix adhesion. Each is linked with ARSJ in more than 11 cancer types. Because this analysis shows association rather than direction, both ARSJ-to-partner and partner-to-ARSJ results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Neuropilin signaling pathway grouped by ARSJ-low versus ARSJ-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARSJ→partner) and Y-score (partner→ARSJ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Neuropilin signaling pathway →	+0.228	+2.253	<.001	<.001	3	12
BONE	Protein localization to early endosome →	+0.330	+2.899	<.001	<.001	3	11
BONE	Regulation of cell-matrix adhesion →	+0.138	+2.368	<.001	<.001	3	11
BONE	Positive regulation of cytoskeleton organization →	+0.085	+2.394	<.001	<.001	3	11
BONE	Protein lipidation →	+0.141	+2.703	<.001	<.001	3	11
SOFT_TISSUE	Axon extension involved in axon guidance →	+1.060	+2.177	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,563 associations by consensus.

Neuropilin signaling pathway by ARSJ expression — BONE

Explore this box plot interactively →