Across TCGA patient cohorts, ARSI mutation is significantly associated with the RNA expression of many other genes, with 1,255 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARSI-associated genes across cancer lineages are LINC02451, OR51V1, and EIF3JP1. Each is linked with ARSI in more than 1 cancer types. Because this analysis shows association rather than direction, both ARSI-to-partner and partner-to-ARSI results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARSI→partner) and Y-score (partner→ARSI) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	LINC02451 →	+0.067	+5.038	<.001	.009	3	2
CESC	OR51V1 →	+0.027	+4.969	.001	.004	3	2
CESC	EIF3JP1 →	+0.212	+4.364	<.001	.006	3	2
COAD	CORO1CP1 →	+0.110	+3.779	.009	.003	3	2
LUAD	MIR4445 →	+0.534	+5.584	<.001	.002	3	2
UCEC	B3GALNT2 →	+0.479	+1.673	.008	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,255 associations by consensus.

Exploration

ARSI survival (RNA) · tumor vs normal (RNA) · all ARSI data types