ARSF

Across TCGA cell cohorts, ARSF mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ARSF-associated genes across cancer lineages are SMIM9, PCARE, and OR5P3. Each is linked with ARSF in more than 1 cancer types. Because this analysis shows association rather than direction, both ARSF-to-partner and partner-to-ARSF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SMIM9 grouped by ARSF-low versus ARSF-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARSF→partner) and Y-score (partner→ARSF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	SMIM9 →	+0.031	+3.734	<.001	.006	3	2
BLOOD_Leukemia	PCARE →	+0.028	+5.201	<.001	.006	3	1
BLOOD_Leukemia	OR5P3 →	+0.125	+5.201	<.001	.006	3	1
BLOOD_Leukemia	FAM9A →	+0.019	+5.539	<.001	.003	3	1
BLOOD_Leukemia	AADACL2 →	+0.012	+4.922	.003	.009	3	1
BLOOD_Leukemia	IZUMO3 →	+0.073	+5.969	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

SMIM9 by ARSF expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →