ARRDC4

Across TCGA patient cohorts, ARRDC4 mutation is significantly associated with the RNA expression of many other genes, with 2,448 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARRDC4-associated genes across cancer lineages are RN7SL248P, LCEP1, and RNA5SP419. Each is linked with ARRDC4 in more than 2 cancer types. Because this analysis shows association rather than direction, both ARRDC4-to-partner and partner-to-ARRDC4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by ARRDC4-low versus ARRDC4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARRDC4→partner) and Y-score (partner→ARRDC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL248P →	+0.048	+2.847	<.001	.008	3	3
STAD	LCEP1 →	+0.189	+5.463	<.001	.005	3	2
LUSC	RNA5SP419 →	+0.732	+6.102	<.001	.001	3	2
LUSC	RNA5SP422 →	+0.804	+5.733	<.001	.001	3	2
UCEC	RNA5SP420 →	+0.564	+2.137	<.001	<.001	3	2
LUSC	RNA5SP415 →	+0.675	+5.733	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,448 associations by consensus.

RN7SL248P by ARRDC4 expression — UCEC

Explore this box plot interactively →