ARPP19P1

Across TCGA patient cohorts, ARPP19P1 mutation is significantly associated with the RNA expression of many other genes, with 28 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARPP19P1-associated genes across cancer lineages are MIR6853, RNU6-28P, and RNU6-23P. Each is linked with ARPP19P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARPP19P1-to-partner and partner-to-ARPP19P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6853 grouped by ARPP19P1-low versus ARPP19P1-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARPP19P1→partner) and Y-score (partner→ARPP19P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MIR6853 →	+0.488	+7.930	<.001	.008	3	1
UCEC	RNU6-28P →	+0.801	+4.499	<.001	.005	3	1
UCEC	RNU6-23P →	+0.810	+4.552	<.001	.005	3	1
UCEC	MIR615 →	+0.925	+5.302	<.001	.001	3	1
UCEC	RNU6ATAC29P →	+1.032	+4.748	<.001	.003	3	1
UCEC	RNU2-68P →	+0.676	+4.302	.003	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

MIR6853 by ARPP19P1 expression — LUAD

Explore this box plot interactively →