ARPIN-AP3S2

Across TCGA patient cohorts, ARPIN-AP3S2 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,155 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible ARPIN-AP3S2-associated GO terms across cancer lineages are Negative regulation of macroautophagy, Ribosome-associated ubiquitin-dependent protein catabolic process, and Citrate metabolic process. Each is linked with ARPIN-AP3S2 in more than 30 cancer types. Because this analysis shows association rather than direction, both ARPIN-AP3S2-to-partner and partner-to-ARPIN-AP3S2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of macroautophagy grouped by ARPIN-AP3S2-low versus ARPIN-AP3S2-high in KICH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARPIN-AP3S2→partner) and Y-score (partner→ARPIN-AP3S2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KICH	Negative regulation of macroautophagy →	+0.054	+0.208	<.001	<.001	3	30
DLBC	Ribosome-associated ubiquitin-dependent protein catabolic process →	+0.095	+0.195	<.001	<.001	2	30
DLBC	Citrate metabolic process →	+0.062	+0.160	<.001	<.001	3	29
DLBC	Regulation of termination of DNA-templated transcription →	+0.080	+0.147	.001	.004	1	31
TGCT	Piecemeal microautophagy of the nucleus →	+0.076	+0.203	<.001	<.001	3	29
SCLC	Vesicle cargo loading →	+0.095	+0.703	.001	.003	2	30

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,155 associations by consensus.

Negative regulation of macroautophagy by ARPIN-AP3S2 expression — KICH

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