ARPIN-AP3S2

Across TCGA pan-cancer cohorts, ARPIN-AP3S2 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated ARPIN-AP3S2 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher ARPIN-AP3S2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ARPIN-AP3S2 expression acts as an unfavorable survival marker, although some lineages such as KIRC and SCLC show a favorable association.

ACC, KIRC, and SCLC are the cancer types where ARPIN-AP3S2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.390	0.755	<.001	88	view →
KIRC	DFS	Median	IV	0.631	0.281	.002	38	view →
SCLC	DFS	Tertile	All	0.656	0.368	.002	25	view →
UCS	DFS	Tertile	IV	0.975	0.401	.024	24	view →
UVM	DFS	Median	All	0.424	0.739	<.001	19	view →
KIRP	DFS	Median	All	0.900	0.809	.013	19	view →
MESO	DFS	Quartile	All	0.122	0.671	.010	12	view →
COAD	OS	Tertile	IV	1.000	0.362	.008	10	view →
GBM	OS	Tertile	All	0.345	0.509	.015	9	view →
LUSC	DFS	Median	IV	0.134	0.827	.014	7	view →
LUAD	DFS	Median	IV	0.235	0.596	.007	6	view →
THYM	DFS	Tertile	II,III,IV	1.000	0.689	.044	5	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

ARPIN-AP3S2–ACC (DFS)

Open the ACC breakdown →