ARPC5L

Across TCGA patient cohorts, ARPC5L mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARPC5L-associated genes across cancer lineages are RNA5-8SP7, RNA5SP51, and RNA5SP223. Each is linked with ARPC5L in more than 1 cancer types. Because this analysis shows association rather than direction, both ARPC5L-to-partner and partner-to-ARPC5L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5-8SP7 grouped by ARPC5L-low versus ARPC5L-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARPC5L→partner) and Y-score (partner→ARPC5L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5-8SP7 →	+0.444	+4.132	<.001	.009	3	1
UCEC	RNA5SP51 →	+0.550	+4.260	<.001	.007	3	1
UCEC	RNA5SP223 →	+0.299	+4.260	<.001	.007	3	1
UCEC	MIR188 →	+0.240	+4.260	.007	.007	3	1
UCEC	TRAJ12 →	+0.869	+2.996	.001	.009	3	1
UCEC	RNU6-908P →	+0.485	+3.386	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

RNA5-8SP7 by ARPC5L expression — UCEC

Explore this box plot interactively →