ARPC4

Across TCGA patient cohorts, ARPC4 protein abundance is significantly associated with the RNA expression of many other genes, with 14,843 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ARPC4-associated genes across cancer lineages are IL4I1, JAK3, and ADGRE2. Each is linked with ARPC4 in more than 5 cancer types. Because this analysis shows association rather than direction, both ARPC4-to-partner and partner-to-ARPC4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARPC4 versus IL4I1 in BRCA, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARPC4→partner) and Y-score (partner→ARPC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	IL4I1 →	+1.249	+0.382	<.001	<.001	3	6
BRCA	JAK3 →	+1.022	+0.432	<.001	<.001	3	6
GBM	ADGRE2 →	+0.658	+0.279	<.001	<.001	3	6
GBM	THEMIS2 →	+0.755	+0.253	<.001	<.001	3	6
COAD	CD72 →	+0.746	+0.302	<.001	<.001	3	6
COAD	TLR2 →	+0.859	+0.201	.001	.005	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,843 associations by consensus.

ARPC4 vs IL4I1 — BRCA

Explore this scatter interactively →