ARPC4

Across TCGA patient cohorts, ARPC4 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARPC4-associated genes across cancer lineages are CD8+ naive T-cells, mv Endothelial cells, and Endothelial cells. Each is linked with ARPC4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARPC4-to-partner and partner-to-ARPC4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ naive T-cells grouped by ARPC4-low versus ARPC4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARPC4→partner) and Y-score (partner→ARPC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ naive T-cells →	+0.029	+3.212	.046	.010	3	1
UCEC	mv Endothelial cells →	-0.030	-3.159	.021	.020	3	1
UCEC	Endothelial cells →	-0.052	-3.127	.013	.020	2	1
UCEC	lymphatic Endothelial cells →	-0.028	-3.129	.033	.019	2	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

CD8+ naive T-cells by ARPC4 expression — UCEC

Explore this box plot interactively →