ARPC4

Across TCGA cell cohorts, ARPC4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,825 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ARPC4-associated GO terms across cancer lineages are C-terminal protein amino acid modification, C-terminal protein lipidation, and Protein import into peroxisome membrane. Each is linked with ARPC4 in more than 12 cancer types. Because this analysis shows association rather than direction, both ARPC4-to-partner and partner-to-ARPC4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C-terminal protein amino acid modification grouped by ARPC4-low versus ARPC4-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARPC4→partner) and Y-score (partner→ARPC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	C-terminal protein amino acid modification →	+0.192	+0.985	.001	.002	3	13
OESOPHAGUS	C-terminal protein lipidation →	+0.200	+1.030	.001	.001	3	11
LUNG_NSCLC_LUSC	Protein import into peroxisome membrane →	+0.115	+0.882	.001	.004	2	11
LUNG_SCLC	tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation →	+0.127	+0.683	<.001	<.001	3	10
BLOOD_Myeloma	Centromeric sister chromatid cohesion →	+0.115	+1.178	.001	<.001	3	10
URINARY_TRACT	Positive regulation of chromosome segregation →	+0.111	+1.022	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,825 associations by consensus.

C-terminal protein amino acid modification by ARPC4 expression — OESOPHAGUS

Explore this box plot interactively →