ARPC3

Across TCGA cell cohorts, ARPC3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,776 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ARPC3-associated GO terms across cancer lineages are Calcium-independent cell-matrix adhesion, Pre-mRNA catabolic process, and Translation reinitiation. Each is linked with ARPC3 in more than 11 cancer types. Because this analysis shows association rather than direction, both ARPC3-to-partner and partner-to-ARPC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Calcium-independent cell-matrix adhesion grouped by ARPC3-low versus ARPC3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARPC3→partner) and Y-score (partner→ARPC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Calcium-independent cell-matrix adhesion →	-0.182	-0.690	.001	<.001	3	12
BONE	Pre-mRNA catabolic process →	-0.190	-0.617	<.001	<.001	3	11
LIVER	Translation reinitiation →	+0.132	+0.488	<.001	.001	3	11
SOFT_TISSUE	Positive regulation of protein autoubiquitination →	-0.213	-0.756	<.001	<.001	3	10
BONE	tRNA transcription by RNA polymerase III →	-0.122	-0.674	.003	.005	3	9
SKIN	DAMP biosynthetic process →	+0.147	+0.705	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,776 associations by consensus.

Calcium-independent cell-matrix adhesion by ARPC3 expression — BONE

Explore this box plot interactively →