ARNT

Across TCGA patient cohorts, ARNT RNA expression is significantly associated with the protein abundance of many other proteins, with 14,981 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ARNT-associated proteins across cancer lineages are GATAD2B, OTUD7B, and ZNF687. Each is linked with ARNT in more than 6 cancer types. Because this analysis shows association rather than direction, both ARNT-to-partner and partner-to-ARNT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARNT versus GATAD2B in PDAC, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ARNT→partner) and Y-score (partner→ARNT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	GATAD2B →	+0.292	+0.358	<.001	<.001	3	7
HNSC	OTUD7B →	+0.348	+0.572	<.001	<.001	3	6
HNSC	ZNF687 →	+0.275	+0.348	.003	.006	3	5
UCEC	RPRD2 →	+0.346	+0.752	<.001	<.001	3	5
UCEC	PRUNE1 →	+0.424	+0.597	<.001	<.001	3	5
LSCC	POGZ →	+0.219	+0.275	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,981 associations by consensus.

ARNT vs GATAD2B — PDAC

Explore this scatter interactively →