ARNT

Across TCGA cell cohorts, ARNT RNA expression is significantly associated with the go_rna of many other GO terms, with 3,886 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ARNT-associated GO terms across cancer lineages are Regulation of protein sumoylation, Positive regulation of protein sumoylation, and Positive regulation of TORC2 signaling. Each is linked with ARNT in more than 17 cancer types. Because this analysis shows association rather than direction, both ARNT-to-partner and partner-to-ARNT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein sumoylation grouped by ARNT-low versus ARNT-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARNT→partner) and Y-score (partner→ARNT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Regulation of protein sumoylation →	+0.129	+0.698	<.001	<.001	3	18
SOFT_TISSUE	Positive regulation of protein sumoylation →	+0.116	+1.078	<.001	<.001	3	16
STOMACH	Positive regulation of TORC2 signaling →	+0.143	+0.825	<.001	.003	3	16
STOMACH	Retrograde transport, endosome to Golgi →	+0.076	+0.729	.001	.006	2	17
KIDNEY	Cytosolic transport →	+0.094	+1.017	<.001	<.001	3	16
LIVER	Positive regulation of hormone biosynthetic process →	+0.266	+1.040	.001	.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,886 associations by consensus.

Regulation of protein sumoylation by ARNT expression — SKIN

Explore this box plot interactively →