ARMT1

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, ARMT1 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated ARMT1 data layer compared with 25 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher ARMT1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated ARMT1 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

OV, UCEC, and LUSC are the cancer types where ARMT1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
OVDFSMedianAll0.1320.541.0236view →
UCECDFSMedianII,III,IV1.0000.311.0404view →
LUSCOSMedianII,III,IV0.2650.631.0483view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

ARMT1–OV (DFS)

Kaplan–Meier survival curve for ARMT1 mutant vs wild-type samples in OV.

Open the OV breakdown →

Exploration