ARMT1

Across TCGA patient cohorts, ARMT1 mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARMT1-associated genes across cancer lineages are INPP4B, EGFR_pY1068, and ERK2. Each is linked with ARMT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARMT1-to-partner and partner-to-ARMT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, INPP4B grouped by ARMT1-low versus ARMT1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARMT1→partner) and Y-score (partner→ARMT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	INPP4B →	-0.386	-2.209	.004	.011	3	2
UCEC	EGFR_pY1068 →	-0.266	-2.459	.012	.019	3	1
UCEC	ERK2 →	+0.165	+1.700	.044	.044	3	1
UCEC	GATA6 →	-0.179	-2.577	.013	.011	3	1
UCEC	Heregulin →	-0.135	-2.459	.009	.019	3	1
UCEC	JNK2 →	+0.186	+3.026	.027	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

INPP4B by ARMT1 expression — UCEC

Explore this box plot interactively →