ARMT1

Across TCGA cell cohorts, ARMT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,211 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ARMT1-associated GO terms across cancer lineages are Negative regulation of ubiquitin protein ligase activity, 7-methylguanosine mRNA capping, and 7-methylguanosine RNA capping. Each is linked with ARMT1 in more than 13 cancer types. Because this analysis shows association rather than direction, both ARMT1-to-partner and partner-to-ARMT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of ubiquitin protein ligase activity grouped by ARMT1-low versus ARMT1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARMT1→partner) and Y-score (partner→ARMT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of ubiquitin protein ligase activity →	+0.235	+0.803	<.001	<.001	3	14
LUNG_NSCLC_LUSC	7-methylguanosine mRNA capping →	+0.111	+1.102	.002	.004	3	13
LUNG_NSCLC_LUSC	7-methylguanosine RNA capping →	+0.111	+1.102	.002	.004	3	13
LARGE_INTESTINE	Negative regulation of meiotic nuclear division →	+0.166	+0.695	<.001	.002	3	12
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair via homologous recombination →	+0.073	+0.713	.002	.003	3	11
BLOOD_Myeloma	Positive regulation of mitochondrial ATP synthesis coupled electron transport →	+0.172	+1.023	.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,211 associations by consensus.

Negative regulation of ubiquitin protein ligase activity by ARMT1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →