ARMT1

Across TCGA cell cohorts, ARMT1 mutation is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ARMT1-associated genes across cancer lineages are MYL2, IFNG, and IFNA6. Each is linked with ARMT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARMT1-to-partner and partner-to-ARMT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYL2 grouped by ARMT1-low versus ARMT1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARMT1→partner) and Y-score (partner→ARMT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MYL2 →	+0.713	+4.152	<.001	.009	3	1
BLOOD_Leukemia	IFNG →	+0.293	+4.152	<.001	.009	3	1
BLOOD_Leukemia	IFNA6 →	+0.263	+5.060	<.001	.001	3	1
BLOOD_Leukemia	MMP20 →	+0.046	+4.705	.003	.003	3	1
BLOOD_Leukemia	SPIC →	+1.052	+5.269	<.001	<.001	3	1
BLOOD_Leukemia	WFDC12 →	+0.244	+4.874	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

MYL2 by ARMT1 expression — BLOOD_Leukemia

Explore this box plot interactively →