ARMS2

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ARMS2 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARMS2-associated genes across cancer lineages are Mesangial cells and Basophils. Each is linked with ARMS2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARMS2-to-partner and partner-to-ARMS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mesangial cells grouped by ARMS2-low versus ARMS2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARMS2→partner) and Y-score (partner→ARMS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMesangial cells →-0.054-2.983.014.03631
UCECBasophils →+0.271+3.000.005.03631
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Mesangial cells by ARMS2 expression — UCEC

Box plot of Mesangial cells in ARMS2-low vs ARMS2-high samples in UCEC.

Explore this box plot interactively →

Exploration