ARMS2

Across TCGA cell cohorts, ARMS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,027 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ARMS2-associated GO terms across cancer lineages are Focal adhesion assembly, Alpha-beta T cell activation involved in immune response, and T cell differentiation involved in immune response. Each is linked with ARMS2 in more than 6 cancer types. Because this analysis shows association rather than direction, both ARMS2-to-partner and partner-to-ARMS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Focal adhesion assembly grouped by ARMS2-low versus ARMS2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARMS2→partner) and Y-score (partner→ARMS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Focal adhesion assembly →	+0.099	+0.103	.001	.003	3	7
BREAST	Alpha-beta T cell activation involved in immune response →	+0.099	+0.048	<.001	.005	3	5
BREAST	T cell differentiation involved in immune response →	+0.099	+0.048	<.001	.005	3	5
OVARY	Negative regulation of protein catabolic process →	+0.067	+0.040	<.001	.007	3	5
BREAST	Negative regulation of canonical NF-kappaB signal transduction →	+0.032	+0.080	.008	.009	3	5
LUNG_NSCLC_LUAD	Proteoglycan catabolic process →	+0.074	+0.068	.008	.007	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,027 associations by consensus.

Focal adhesion assembly by ARMS2 expression — LUNG_SCLC

Explore this box plot interactively →