ARMH3

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ARMH3 mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ARMH3-associated genes across cancer lineages are ODF1, OR14A2, and SPACA1. Each is linked with ARMH3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARMH3-to-partner and partner-to-ARMH3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ODF1 grouped by ARMH3-low versus ARMH3-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARMH3→partner) and Y-score (partner→ARMH3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OESOPHAGUSODF1 →+0.996+4.906<.001.00631
BREASTOR14A2 →+0.032+5.169<.001.00531
OVARYSPACA1 →+0.017+4.807<.001.00331
OVARYNPBWR2 →+0.066+4.029<.001.00931
OVARYCCL19 →+0.060+4.029.002.00931
BLOOD_LymphomaBMX →+0.837+4.350<.001.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

ODF1 by ARMH3 expression — OESOPHAGUS

Box plot of ODF1 in ARMH3-low vs ARMH3-high samples in OESOPHAGUS.

Explore this box plot interactively →

Exploration