ARMCX5-GPRASP2

Across TCGA pan-cancer cohorts, ARMCX5-GPRASP2 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated ARMCX5-GPRASP2 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher ARMCX5-GPRASP2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ARMCX5-GPRASP2 expression acts as an unfavorable survival marker, although some lineages such as UCS and KIRC show a favorable association.

KICH, UVM, and KIRP are the cancer types where ARMCX5-GPRASP2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Quartile	II,III,IV	0.397	0.957	.001	66	view →
UVM	DFS	Median	III,IV	0.249	0.719	.001	60	view →
KIRP	DFS	Tertile	All	0.769	0.932	<.001	57	view →
UCS	DFS	Tertile	II,III,IV	0.647	0.187	<.001	48	view →
KIRC	DFS	Median	All	0.861	0.721	<.001	47	view →
LIHC	OS	Tertile	All	0.685	0.832	<.001	32	view →
SCLC	DFS	Median	II,III,IV	0.599	0.311	.005	21	view →
LGG	OS	Quartile	All	0.674	0.913	<.001	21	view →
ACC	DFS	Median	All	0.555	0.886	.001	21	view →
BLCA	OS	Median	II,III,IV	0.672	0.742	.027	16	view →
OV	DFS	Median	II,III,IV	0.580	0.498	.014	14	view →
BRCA	DFS	Median	III,IV	0.931	0.821	.011	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

ARMCX5-GPRASP2–KICH (DFS)

Open the KICH breakdown →