ARMCX5-GPRASP2

Across TCGA pan-cancer cohorts, ARMCX5-GPRASP2 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of ARMCX5-GPRASP2’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where ARMCX5-GPRASP2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ARMCX5-GPRASP2 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

HNSC, THCA, and KICH are the cancer types where ARMCX5-GPRASP2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ARMCX5-GPRASP2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	III,IV	+0.465	<.001	11	view →
THCA	All	All	−0.361	<.001	9	view →
KICH	Female	All	−0.995	<.001	7	view →
LIHC	Male	All	+0.507	<.001	7	view →
UCEC	All	All	−0.616	<.001	6	view →
CHOL	Male	All	+1.461	<.001	5	view →
LUSC	Male	All	+0.403	<.001	4	view →
LUAD	All	All	+0.285	<.001	4	view →
KIRP	Male	All	−0.237	.039	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

ARMCX5-GPRASP2–HNSC

Open the HNSC breakdown →