ARMC8

Across TCGA pan-cancer cohorts, ARMC8 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated ARMC8 data layer compared with 26 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher ARMC8 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated ARMC8 expression acts as an unfavorable survival marker.

DLBC and LIHC are the cancer types where ARMC8 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	DFS	Median	II,III,IV	0.022	0.837	<.001	12	view →
LIHC	OS	Median	All	0.015	0.784	<.001	9	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

ARMC8–DLBC (DFS)

Open the DLBC breakdown →