ARMC7

Across TCGA cell cohorts, ARMC7 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,704 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ARMC7-associated GO terms across cancer lineages are Negative regulation of DNA-templated transcription, elongation, Negative regulation of transcription elongation by RNA polymerase II, and Endosomal vesicle fusion. Each is linked with ARMC7 in more than 12 cancer types. Because this analysis shows association rather than direction, both ARMC7-to-partner and partner-to-ARMC7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of DNA-templated transcription, elongation grouped by ARMC7-low versus ARMC7-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARMC7→partner) and Y-score (partner→ARMC7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Negative regulation of DNA-templated transcription, elongation →	+0.105	+0.742	.008	.003	3	13
KIDNEY	Negative regulation of transcription elongation by RNA polymerase II →	+0.112	+0.836	<.001	.004	3	12
LIVER	Endosomal vesicle fusion →	+0.126	+1.169	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Positive regulation of transcription initiation by RNA polymerase II →	+0.081	+0.987	<.001	<.001	3	10
BONE	Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.183	+0.577	.001	.002	3	10
BLOOD_Leukemia	Autophagosome-lysosome fusion →	+0.082	+0.533	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,704 associations by consensus.

Negative regulation of DNA-templated transcription, elongation by ARMC7 expression — LIVER

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