ARMC7

Across TCGA pan-cancer cohorts, ARMC7 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of ARMC7’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where ARMC7 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ARMC7 is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

HNSC, KIRC, and KICH are the cancer types where ARMC7 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ARMC7 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	IV	+1.383	<.001	12	view →
KIRC	Female	II,III,IV	−0.805	<.001	12	view →
KICH	Male	All	−2.193	<.001	11	view →
LIHC	Male	II,III,IV	+1.218	<.001	9	view →
BLCA	All	All	+0.913	.001	9	view →
STAD	All	II,III,IV	+1.077	<.001	8	view →
BRCA	All	III,IV	+0.624	<.001	6	view →
CHOL	Male	All	+1.878	<.001	5	view →
THCA	Male	II,III,IV	−0.454	.007	5	view →
COAD	All	All	−0.288	.001	4	view →
PRAD	All	All	−0.205	.024	2	view →
ESCA	All	All	+0.915	.035	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

ARMC7–HNSC

Open the HNSC breakdown →