ARMC4

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, ARMC4 mass-spec protein is linked to patient survival in 1 of 34 cancer types, making it a survival-associated ARMC4 data layer compared with 22 for mass-spec protein and 11 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher ARMC4 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated ARMC4 expression acts as an unfavorable survival marker.

LSCC are the cancer types where ARMC4 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LSCCOSMedianAll0.9131.000.0075view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

ARMC4–LSCC (OS)

Kaplan–Meier survival curve for ARMC4 mass-spec protein-high vs -low samples in LSCC.

Open the LSCC breakdown →

Exploration