ARMC4

Across TCGA cell cohorts, ARMC4 mutation is significantly associated with the RNA expression of many other genes, with 1,010 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ARMC4-associated genes across cancer lineages are PPP2CB, NCS1, and CAPN7. Each is linked with ARMC4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARMC4-to-partner and partner-to-ARMC4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PPP2CB grouped by ARMC4-low versus ARMC4-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARMC4→partner) and Y-score (partner→ARMC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PPP2CB →	+0.493	+1.721	.005	.003	3	2
LARGE_INTESTINE	NCS1 →	+1.098	+2.130	<.001	<.001	3	2
LARGE_INTESTINE	CAPN7 →	+0.430	+2.299	.001	.001	3	2
LARGE_INTESTINE	PGBD1 →	+0.744	+2.130	<.001	<.001	3	2
LARGE_INTESTINE	NEK1 →	+0.585	+3.169	<.001	.006	3	2
LARGE_INTESTINE	AZIN2 →	+0.693	+2.222	.003	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,010 associations by consensus.

PPP2CB by ARMC4 expression — LARGE_INTESTINE

Explore this box plot interactively →