ARMC3

Across TCGA patient cohorts, ARMC3 mutation is significantly associated with the RNA expression of many other genes, with 3,621 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARMC3-associated genes across cancer lineages are WDR62, NUDC, and CFB. Each is linked with ARMC3 in more than 2 cancer types. Because this analysis shows association rather than direction, both ARMC3-to-partner and partner-to-ARMC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, WDR62 grouped by ARMC3-low versus ARMC3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARMC3→partner) and Y-score (partner→ARMC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	WDR62 →	+0.723	+4.021	<.001	<.001	3	3
UCEC	NUDC →	+0.377	+1.673	.003	.003	3	3
UCEC	CFB →	-1.321	-2.252	<.001	<.001	3	3
BRCA	OR6R2P →	+0.136	+3.833	<.001	.004	3	2
BRCA	MIR6738 →	+0.564	+3.569	.001	.004	3	2
CESC	RNA5SP432 →	+0.329	+5.539	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,621 associations by consensus.

WDR62 by ARMC3 expression — UCEC

Explore this box plot interactively →