ARMC3

Across TCGA cell cohorts, ARMC3 mutation is significantly associated with the RNA expression of many other genes, with 40 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ARMC3-associated genes across cancer lineages are OR1Q1, OR10K1, and PROP1. Each is linked with ARMC3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARMC3-to-partner and partner-to-ARMC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1Q1 grouped by ARMC3-low versus ARMC3-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARMC3→partner) and Y-score (partner→ARMC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	OR1Q1 →	+0.343	+3.750	<.001	.007	3	2
BLOOD_Leukemia	OR10K1 →	+0.432	+4.234	.001	.003	3	2
BLOOD_Leukemia	PROP1 →	+0.025	+3.874	<.001	.005	3	2
LARGE_INTESTINE	ODF2 →	+0.642	+3.064	.003	.009	3	1
LARGE_INTESTINE	OR10A5 →	+0.043	+2.672	.001	.004	3	1
LARGE_INTESTINE	HMX3 →	+0.453	+3.531	.003	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

OR1Q1 by ARMC3 expression — BREAST

Explore this box plot interactively →