ARMC2

Across TCGA patient cohorts, ARMC2 mutation is significantly associated with the RNA expression of many other genes, with 2,079 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARMC2-associated genes across cancer lineages are LSP1P1, UBE2V1P4, and MIR6783. Each is linked with ARMC2 in more than 2 cancer types. Because this analysis shows association rather than direction, both ARMC2-to-partner and partner-to-ARMC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LSP1P1 grouped by ARMC2-low versus ARMC2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARMC2→partner) and Y-score (partner→ARMC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	LSP1P1 →	+0.393	+3.373	.004	.004	3	3
LUSC	UBE2V1P4 →	+0.116	+6.102	<.001	.001	3	3
LIHC	MIR6783 →	+0.586	+5.268	<.001	.006	3	2
CESC	MIR549A →	+0.266	+4.757	<.001	.004	3	2
UCEC	HMGXB4 →	+0.388	+1.595	.008	.006	3	2
UCEC	NDUFAF5 →	+0.304	+1.856	.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,079 associations by consensus.

LSP1P1 by ARMC2 expression — COAD

Explore this box plot interactively →